It is impossible for a lesser creature to understand a more advanced one. How can anything understand something more complex and advanced than itself? For a flea to understand a dog it would have to be at least as advanced as a dog. For a dog to understand a man it would have to be at least as advanced as a man. How much greater distance is there between Creator and creature. Man can imagine what God might be like, and people have plenty of ideas about Him. Almost everyone has an opinion as to what God is or is not like, or as to whether He even exists. But man's opinions are irrelevant, because they can never be more than speculations. By his own resources the creature cannot possibly comprehend his Creator.
John MacArthur