When Jesus said, “take up your cross” to them, they thought of a cruel instrument of torture and death. They thought of dying in the most agonizing method known to man. They thought of poor, condemned criminals hanging on crosses by the roadside. Doubtless they had seen men executed in that fashion. They understood He was calling them to die for Him. They knew He was asking them to make the ultimate sacrifice, to surrender to Him as Lord in every sense.
John MacArthur