The universal problem of guilt is not just a problem of how to feel better, but how to be right with God. The secular devices to lessen the misery of our guilt will always fail sooner or later because they ignore the main problem of human existence. We are guilty before God. It is His law we have broken. It is His glory from which we fall so short (Romans 3:23). Every person in this [world] is personally accountable to God and will meet Him some day either guilty and condemned, or acquitted and destined for joy.
John Piper