Frankly, the deepest pain you'll ever know and the deepest pain I'll ever know is not physical. It's not material. It doesn't have to do with our physical body and it doesn't have to do with our material or economic or circumstantial life patterns. The greatest pain we will ever know is relational. It is the potential of people to devastate us, to destroy us, to abuse us. And apart from internal personal guilt which has to be the greatest pain but that is personal and internal, the most serious pain we suffer in the world comes from unfulfilled and devastated relationships. No disease is as painful as rejection. No disease is as painful as false accusation. No disease is as painful as misrepresentation, betrayal [and] hatred.